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Found 17 of ic50 for monomerid = 50049395
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  252nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length MNK2 expressed in baculovirus expression system incubated for 1 hr by Kinase Tracer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  490nMAssay Description:Inhibition of porcine DPP4 after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 0 group B member 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50: >834nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of GST-tagged recombinant human full length MNK1 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of recombinant His6-tagged Pim-1 (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard Karls University of Tuebingen

LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  1.86E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  3.32E+4nMAssay Description:Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls University of Tuebingen

LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  3.48E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  4.62E+4nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  4.63E+4nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  4.66E+4nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroidogenic factor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50: >6.75E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay