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Found 11 of ic50 for monomerid = 50083351
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]Ifenprodil from NMDA receptor GluN2B subunit in Wistar rat cerebral cortexMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  47nMAssay Description:Displacement of [3H]ifenprodil from Wistar rat cerebral cortex GluN2B receptor after 120 minsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
I2Bm

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  66nMAssay Description:Antagonist activity at NR1/NR2B receptor assessed as inhibition of Glu/Gly induced Ca2+ influxMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  110nMAssay Description:Negative allosteric modulation of human GluN2B receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
I2Bm

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  177nMAssay Description:Antagonist activity against NR1a/NR2B receptor transfected in human HEK293 cells assessed as inhibition of NMDA-induced Ca2+ influxMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
I2Bm

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at wild type NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude by two-el...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
I2Bm

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  340nMAssay Description:Antagonist activity against NR1/NR2B receptor expressed in xenopus oocytes assessed as inhibition of NMDA induced Ca2+ influxMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  2.91E+4nMAssay Description:Negative allosteric modulation of human GluN2C receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  3.95E+4nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataIC50:  7.59E+4nMAssay Description:Negative allosteric modulation of human GluN2D receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed