Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 50100305
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50100305(2-(2,4-Dichloro-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50:  8nMAssay Description:Inhibition of rate of incorporation of [3H]-FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50100305(2-(2,4-Dichloro-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50:  260nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in cultured v-Ha-ras-transformed RAT1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50100305(2-(2,4-Dichloro-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50:  280nMAssay Description:Inhibition of rate of incorporation of [3H]-GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-tran...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed