Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 4 of ic50 for monomerid = 50154255
TargetEpidermal growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM50154255(CHEMBL3774926 | US10106508, Compound II-1)
Affinity DataIC50: <50nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEpidermal growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM50154255(CHEMBL3774926 | US10106508, Compound II-1)
Affinity DataIC50:  139nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [T790M](Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM50154255(CHEMBL3774926 | US10106508, Compound II-1)
Affinity DataIC50: <300nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154255(CHEMBL3774926 | US10106508, Compound II-1)
Affinity DataIC50:  880nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed