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Found 5 of ic50 for monomerid = 50241837
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50241837(CHEMBL4102913 | US10626113, Compound G | US1089975...)
Affinity DataIC50:  1.55nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50241837(CHEMBL4102913 | US10626113, Compound G | US1089975...)
Affinity DataIC50:  1.55nMAssay Description:A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50241837(CHEMBL4102913 | US10626113, Compound G | US1089975...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant PDE5A1 using FAM-labelled cGMP as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50241837(CHEMBL4102913 | US10626113, Compound G | US1089975...)
Affinity DataIC50: >100nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50241837(CHEMBL4102913 | US10626113, Compound G | US1089975...)
Affinity DataIC50: >100nMAssay Description:A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react...More data for this Ligand-Target Pair
In DepthDetails US Patent