Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 50247925
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50247925(1-(((R)-3-methyl-4-(4-((R)-1,1,1-trifluoro-2-hydro...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50247925(1-(((R)-3-methyl-4-(4-((R)-1,1,1-trifluoro-2-hydro...)
Affinity DataIC50:  128nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50247925(1-(((R)-3-methyl-4-(4-((R)-1,1,1-trifluoro-2-hydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50247925(1-(((R)-3-methyl-4-(4-((R)-1,1,1-trifluoro-2-hydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed