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Found 21 of ic50 for monomerid = 50269847
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50:  0.940nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50:  1.20nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged P300 measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50:  17nMAssay Description:Inhibition of CBP in human PBMC derived naive CD4-positive T cells assessed as decrease in FOXP3 mRNA level in Treg cells measured after 4 days by qu...More data for this Ligand-Target Pair
TargetPeregrin(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50:  4.60E+3nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged BRPF1 measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50:  5.10E+3nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged BRD4 bromodomain-1 measured after 10 mins by TR-FRET assa...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50:  1.20E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged BRD4 bromodomain-2 measured after 10 mins by TR-FRET assa...More data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >1.80E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged BAZ2B measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged TAF1 bromodomain-1 measured after 10 mins by TR-FRET assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 9(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged BRD9 measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CECR2 measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from recombinant His-tagged BPTF (unknown origin) measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 8(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from recombinant His-tagged BRD8 bromodomain-1 (unknown origin) measured after 10 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from recombinant His-tagged TAF1 bromodomain-2 (unknown origin) measured after 10 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged PCAF measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from recombinant His-tagged human GCN5L2 measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed