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Report error Found 3 of ic50 for monomerid = 50342184
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342184(CHEMBL1766185 | rac-N-[4'-[Cyclopropyl(hydroxy)-1H...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human 17,20 lyase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342184(CHEMBL1766185 | rac-N-[4'-[Cyclopropyl(hydroxy)-1H...)
Affinity DataIC50:  81nMAssay Description:Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342184(CHEMBL1766185 | rac-N-[4'-[Cyclopropyl(hydroxy)-1H...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of human CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed