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Found 4 of ic50 for monomerid = 50382376
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382376(CHEMBL114057)
Affinity DataIC50:  800nMAssay Description:Inhibition of p38alpha kinase using KRELVEPLTPSGEAPNQALLR as substrate for 20 mins by lactate dehydrogenase-coupled spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50382376(CHEMBL114057)
Affinity DataIC50:  800nMAssay Description:Binding affinity against p38 MAP kinase systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382376(CHEMBL114057)
Affinity DataIC50:  970nMAssay Description:Inhibition of p38alpha in human PBMC assessed as inhibition of LPS-induced IL1beta production after 16 to 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382376(CHEMBL114057)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of p38alpha in human PBMC assessed as inhibition of LPS-induced TNFalpha production after 16 to 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed