TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 236nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as reduction in S35-MK-0499 bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human liver microsomes CYP2C9 using diclofenac as substrate by MUX-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of human liver microsomes CYP2D6 using dextromethorphan as substrate by MUX-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver microsomes CYP3A4 using testosterone as substrate by MUX-MS/MS analysisMore data for this Ligand-Target Pair
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