Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ki for monomerid = 50022184
TargetCarbonic anhydrase 9(Homo sapiens (Human))
S.G.S.I.T.S.

LigandPNGBDBM50022184(7,8-Dihydroxy-4-methyl-2H-chromen-2-one (3) | 7,8-...)
Affinity DataKi:  270nM ΔG°:  -34.9kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50022184(7,8-Dihydroxy-4-methyl-2H-chromen-2-one (3) | 7,8-...)
Affinity DataKi:  2.11E+3nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
S.G.S.I.T.S.

LigandPNGBDBM50022184(7,8-Dihydroxy-4-methyl-2H-chromen-2-one (3) | 7,8-...)
Affinity DataKi:  6.60E+3nM ΔG°:  -27.5kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
S.G.S.I.T.S.

LigandPNGBDBM50022184(7,8-Dihydroxy-4-methyl-2H-chromen-2-one (3) | 7,8-...)
Affinity DataKi:  8.70E+3nM ΔG°:  -26.8kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
S.G.S.I.T.S.

LigandPNGBDBM50022184(7,8-Dihydroxy-4-methyl-2H-chromen-2-one (3) | 7,8-...)
Affinity DataKi: >2.00E+5nM ΔG°: >-19.6kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed