Compile Data Set for Download or QSAR
maximum 50k data
Found 19 of ki for monomerid = 50105085
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H]DAMGO from human opioid gamma receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  0.980nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  0.980nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  0.980nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  1.30nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]U-69593 from human opioid kappa receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  3.90nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  14.3nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  14.3nMAssay Description:Specific binding is determined by subtraction of the cpm bound in the presence of 50-100× excess of cold ligand. Binding data assays were analyzed us...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  25.9nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  29.9nMAssay Description:Specific binding is determined by subtraction of the cpm bound in the presence of 50-100× excess of cold ligand. Binding data assays were analyzed us...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]naltrindole from human opioid delta receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  319nMAssay Description:Specific binding is determined by subtraction of the cpm bound in the presence of 50-100× excess of cold ligand. Binding data assays were analyzed us...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  319nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank