Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibition of PTP1B using fluorescein 3,6 diphosphate as substrate measured for 1 hr in presence of 1 mM dithiothreitolMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of PTP1B using fluorescein 3,6 diphosphate as substrate measured for 1 hr in presence of 1 mM dithiothreitolMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of PTP1B using fluorescein 3,6 diphosphate as substrate measured for 1 hr in presence of 1 mM dithiothreitolMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of PTP1B using fluorescein 3,6 diphosphate as substrate measured for 1 hr in presence of 1 mM dithiothreitolMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ADAMTS-4 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ADAMTS-4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMpH: 8.0Assay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of PTP1B using fluorescein 3,6 diphosphate as substrate measured for 1 hr in presence of 1 mM dithiothreitolMore data for this Ligand-Target Pair
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of VHR using fluorescein 3,6 diphosphate as substrate measured for 1 hr in presence of 1 mM dithiothreitolMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.81E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.01E+4nMAssay Description:Inhibition of MBP-fused recombinant wild type CDC25B3 using fluorescein 3,6 diphosphate as substrate measured for 30 mins in presence of 1 mM dithiot...More data for this Ligand-Target Pair
Affinity DataIC50: 4.06E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of PTP1B using fluorescein 3,6 diphosphate as substrate measured for 1 hr in presence of 1 mM dithiothreitolMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of PTP1B using fluorescein 3,6 diphosphate as substrate measured for 1 hr in presence of 1 mM dithiothreitolMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of MBP-fused recombinant wild type CDC25B3 using fluorescein 3,6 diphosphate as substrate measured for 30 mins in presence of 1 mM dithiot...More data for this Ligand-Target Pair
Affinity DataIC50: 5.73E+4nMAssay Description:Inhibition of MBP-fused recombinant wild type CDC25B3 using fluorescein 3,6 diphosphate as substrate measured for 30 mins in presence of 1 mM dithiot...More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 6.29E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of matriptase (unknown origin) using Boc-Gln-Ala-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 7.58E+4nMAssay Description:Inhibition of VHR using fluorescein 3,6 diphosphate as substrate measured for 1 hr in presence of 1 mM dithiothreitolMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of human kallikrein14 using Boc-Val-Pro-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human kallikrein7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of human kallikrein14 using Boc-Val-Pro-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of matriptase (unknown origin) using Boc-Gln-Ala-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of human kallikrein14 using Boc-Val-Pro-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair