Compile Data Set for Download or QSAR
maximum 50k data
Found 865 Enz. Inhib. hit(s) with all data for entry = 50015337
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635970((1R,2S)-5'-methoxy-2-(3-{[3-methoxy-2-(morpholin-4...)
Affinity DataIC50:  1.31nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636122(6-chloro-5-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-di...)
Affinity DataIC50:  1.33nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636150((1R,2S)-2-(3-{[4-ethoxy-6-(methanesulfonyl)pyridin...)
Affinity DataIC50:  1.34nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635942((1R,2S)-2-[3-({6-[(2R,6S)-2,6-dimethylmorpholin-4-...)
Affinity DataIC50:  1.34nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636081(5-methoxy-4-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  1.35nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636099((1R,2S)-2-(3-{[5-(ethanesulfonyl)-3-methoxypyridin...)
Affinity DataIC50:  1.35nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636109(6-methoxy-5-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  1.36nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636041((1R,2S)-2-(3-{[2-(3,3-difluoropyrrolidin-1-yl)-5-m...)
Affinity DataIC50:  1.36nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636093(6-methoxy-5-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  1.36nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636133((1R,2S)-2-(3-{[6-(ethanesulfonyl)-4-methoxypyridin...)
Affinity DataIC50:  1.39nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636129((1R,2S)-2-(3-{[5-(cyclopropanesulfonyl)-3-methoxyp...)
Affinity DataIC50:  1.41nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636016((1R,2R)-2-{5-fluoro-3-[(5-methoxy-2-methylpyrimidi...)
Affinity DataIC50:  1.41nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636144((1R,2S)-2-(3-{[3-ethoxy-5-(4-methylpiperazine-1-sa...)
Affinity DataIC50:  1.45nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636018((1R,2S)-2-(3-{[5-(cyclopropylmethoxy)-2-methylpyri...)
Affinity DataIC50:  1.49nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636034((1R,2S)-5'-methoxy-2-{3-[(3-methoxyquinolin-2-yl)a...)
Affinity DataIC50:  1.52nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635983((1R,2S)-2-(3-{[6-(3-hydroxyazetidin-1-yl)-2-(propa...)
Affinity DataIC50:  1.54nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636080((1R,2S)-2-(3-{[6-(ethanesulfonyl)-2-methoxypyridin...)
Affinity DataIC50:  1.54nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636102(6-methoxy-5-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  1.56nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636066((1R,2S)-2-(3-{[5-ethoxy-2-(methylsulfanyl)pyrimidi...)
Affinity DataIC50:  1.56nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636138((1R,2S)-5'-methoxy-2-(3-{[3-methoxy-5-(1,2-oxazoli...)
Affinity DataIC50:  1.57nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635962((1R,2S)-5'-methoxy-2-{3-[(5-methoxy-2-methylpyrimi...)
Affinity DataIC50:  1.58nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636083(2,5-dimethoxy-4-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',...)
Affinity DataIC50:  1.58nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635885((1R,2S)-2-{3-[(2-chloro-5-methoxypyrimidin-4-yl)am...)
Affinity DataIC50:  1.59nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635991((1R,2S)-5'-methoxy-2-(3-{[5-methoxy-2-(oxetan-3-yl...)
Affinity DataIC50:  1.59nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636076((1R,2S)-2-(3-{[6-(dimethylphosphoryl)-2-methoxypyr...)
Affinity DataIC50:  1.64nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636063((1R,2S)-5'-methoxy-2-(3-{[5-methoxy-2-(2-oxa-6-aza...)
Affinity DataIC50:  1.64nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636110(Diastereomer 1: (1R,2S)-2-(3-{[6-(methanesulfinyl)...)
Affinity DataIC50:  1.69nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636071(Diastereomer 1: (1R,2S)-5'-methoxy-2-(3-{[5-methox...)
Affinity DataIC50:  1.71nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635975((1R,2S)-5'-methoxy-2-(3-{[3-methoxy-6-(oxetan-3-yl...)
Affinity DataIC50:  1.73nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635952((1R,2S)-2-[3-({2-cyclopropyl-6-[(2R,6S)-2,6-dimeth...)
Affinity DataIC50:  1.76nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636057((1R,2S)-2-(4-fluoro-3-{[5-methoxy-2-(methylsulfany...)
Affinity DataIC50:  1.78nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635993((1R,2S)-2-(3-{[5-(difluoromethoxy)-2-methylpyrimid...)
Affinity DataIC50:  1.79nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636006((1R,2S)-2-{3-[(5-ethoxy-2-methylpyrimidin-4-yl)ami...)
Affinity DataIC50:  1.79nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636025((1R,2S)-5'-methoxy-2-{3-[(2-methyl-6,7-dihydrofuro...)
Affinity DataIC50:  1.91nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635960((1R,2S)-5'-methoxy-2-(3-{[5-methoxy-6-(morpholin-4...)
Affinity DataIC50:  1.91nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636045((1R,2S)-2-(3-{[2-(3-fluoroazetidin-1-yl)-5-methoxy...)
Affinity DataIC50:  1.92nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636151((1R,2S)-2-(3-{[5-(difluoromethanesulfonyl)-3-metho...)
Affinity DataIC50:  1.93nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636031((1R,2S)-2-{3-[(2-ethyl-5-methoxypyrimidin-4-yl)ami...)
Affinity DataIC50:  1.93nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636028((1R,2S)-2-(3-{[2-(azetidin-1-yl)-5-methoxypyrimidi...)
Affinity DataIC50:  1.95nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636030((1R,2S)-5'-methoxy-2-{3-[(2-methyl-6,7-dihydro-5H-...)
Affinity DataIC50:  1.96nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636056((1R,2S)-2-(3-{[6-(4,4-difluoropiperidine-1-carbony...)
Affinity DataIC50:  1.96nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636039((1R,2S)-2-(3-{[6-(methanesulfonyl)-2-methoxypyridi...)
Affinity DataIC50:  1.97nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636136((1R,2S)-5'-methoxy-2-{3-[(6-methoxy-2-methyl-1-oxo...)
Affinity DataIC50:  1.98nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635902((1R,2S)-2-{3-[(3-hydroxy-2,3-dihydro-1-benzofuran-...)
Affinity DataIC50:  2.08nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635986((1R,2S)-2-(3-{[2-(3-hydroxyazetidin-1yl)-5-methoxy...)
Affinity DataIC50:  2.09nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636086((1R,2S)-5'-methoxy-2-(3-{[2-methoxy-6-(2-oxopyrrol...)
Affinity DataIC50:  2.10nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636084((1R,2S)-2-(3-{[2-(dimethylamino)-6,7-dihydro-5H-cy...)
Affinity DataIC50:  2.13nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636004((1R,2S)-2-(3-{[5-chloro-6-(2-oxa-6-azaspiro[3.3]he...)
Affinity DataIC50:  2.15nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636106((1R,2S)-5'-methoxy-2-(3-{[3-methoxy-5-(3-methoxyaz...)
Affinity DataIC50:  2.17nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636110(Diastereomer 1: (1R,2S)-2-(3-{[6-(methanesulfinyl)...)
Affinity DataIC50:  2.18nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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