Compile Data Set for Download or QSAR
maximum 50k data
Found 20231 Enz. Inhib. hit(s) with all data for entry = 50048085
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517007(N-(3-fluoro-4-((3-((2- hydroxy-2- methylpropyl)ami...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517090((R)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516964(N-(3-fluoro-4-((3-((3- hydroxy-3-methylbutan-2- yl...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517051((R)-5-bromo-N-(3- fluoro-4-((3-((1- hydroxypropan-...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [F1200I](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517047((S)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [1-13,15-1390](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517049((R)-5-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517037((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [D1228H](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517033((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230H](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517033((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517009(N-(3-fluoro-4-((3- (((2R,3R)-3- hydroxybutan-2- yl...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517014((R)-1- (cyclopropylmethyl)-N- (3-fluoro-4-((3-((1-...)
Affinity DataIC50:  1.5nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517090((R)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  1.60nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517034((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.60nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [F1200I](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517099((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  1.60nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [D1228H](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517049((R)-5-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...)
Affinity DataIC50:  1.60nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517034((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.60nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517032((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.60nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [F1200I](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517021((R)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- hydroxypr...)
Affinity DataIC50:  1.60nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517014((R)-1- (cyclopropylmethyl)-N- (3-fluoro-4-((3-((1-...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517006((S)-N-(3-fluoro-4-((3- ((2- hydroxypropyl)amino)- ...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [D1228N](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517030((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [D1228H](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517030((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517022((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [1-13,15-1390](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517002((R)—N-(3-fluoro-4-((3-((1-hydroxypropan-2-yl)amino...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517035((R)-6-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517044((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517050((R)-1-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516981(N-(4-((3-((4,4-difluoro-1- hydroxybutan-2- yl)amin...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517078((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [F1200I](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517078((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516979(N-(3-fluoro-4-((3-((1- hydroxy-4-methoxybutan- 2-y...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [1-13,15-1390](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517011((S)-N-(3-fluoro-4-((3- ((3-hydroxy-3- methylbutan-...)
Affinity DataIC50:  1.70nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516981(N-(4-((3-((4,4-difluoro-1- hydroxybutan-2- yl)amin...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [D1228H](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517051((R)-5-bromo-N-(3- fluoro-4-((3-((1- hydroxypropan-...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [D1228N](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517033((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [D1228H](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517021((R)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- hydroxypr...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [F1200I](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517090((R)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517021((R)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- hydroxypr...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517038((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [1-13,15-1390](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516997((R)-N-(3-fluoro-4-((3- ((1-hydroxybutan-2- yl)amin...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516975(N-(4-((3-((1,3- dihydroxypropan-2- yl)amino)-1H- p...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517006((S)-N-(3-fluoro-4-((3- ((2- hydroxypropyl)amino)- ...)
Affinity DataIC50:  1.80nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517022((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...)
Affinity DataIC50:  1.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517049((R)-5-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...)
Affinity DataIC50:  1.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517049((R)-5-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...)
Affinity DataIC50:  1.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [D1228N](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516967(N-(3-fluoro-4-((3- (((1s,3s)-3- (hydroxymethyl)cyc...)
Affinity DataIC50:  1.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516975(N-(4-((3-((1,3- dihydroxypropan-2- yl)amino)-1H- p...)
Affinity DataIC50:  1.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230S](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM517099((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...)
Affinity DataIC50:  1.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [Y1230C](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM516979(N-(3-fluoro-4-((3-((1- hydroxy-4-methoxybutan- 2-y...)
Affinity DataIC50:  1.90nMAssay Description:The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [658-1114](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM296818(US10112942, Example 553 | US10137124, Example 553 ...)
Affinity DataIC50:  2nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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