Compile Data Set for Download or QSAR
maximum 50k data
Found 81 Enz. Inhib. hit(s) with all data for entry = 11145
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594634(2,7-Diazaspiro[4.5]decane-6,8-dione | US11584748, ...)
Affinity DataKd:  84nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594635(2-Methyl-2,7-diazaspiro[4.5]decane-3,6,8-trione | ...)
Affinity DataKd:  159nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594636((2-(2-Phenylacetyl)-2,7-diazaspiro[4.5]decane-6,8-...)
Affinity DataKd:  369nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594637(2-(2,3-Dihydro-1H-indene-1-carbonyl)-2,7-diazaspir...)
Affinity DataKd:  316nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594638(2-(3-Nitrobenzoyl)-2,7-diazaspiro[4.5]decane-6,8-d...)
Affinity DataKd:  23nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594639(Methyl 6-(6,8-dioxo-2,7-diazaspiro[4.5]decan-2-yl)...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594640(2-(Thiazolo[4,5-b]pyridin-2-yl)-2,7-diazaspiro[4.5...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594641(2-(4-Nitrophenyl)-2,7-diazaspiro[4.5]decane-6,8-di...)
Affinity DataKd:  14nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594642(2-(5-Nitro-1H-benzo[d]imidazol-2-yl)-2,7-diazaspir...)
Affinity DataKd:  8nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594643((+)-2-(4-Nitrophenyl)-2,7-diazaspiro[4.5]decane-6,...)
Affinity DataKd:  1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594644((+2-(4-Nitrophenyl)-2,7-diazaspiro[4.5]decane-6,8-...)
Affinity DataKd:  5nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594645(2-(Benzo[d]thiazol-2-yl)-2,7-diazaspiro[4.5]decane...)
Affinity DataKd:  1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594646(Methyl 2-(6,8-dioxo-2,7-diazaspiro[4.5]decan-2-yl)...)
Affinity DataKd:  96nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594647(Methyl 2-(6,8-dioxo-2,7-diazaspiro[4.5]decan-2-yl)...)
Affinity DataKd:  15nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594648(2-(Quinolin-2-yl)-2,7-diazaspiro[4.5]decane-6,8-di...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594649(2-(6-Aminobenzo[d]thiazol-2-yl)-2,7-diazaspiro[4.5...)
Affinity DataKd:  10nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594650(2-(Oxazolo[4,5-b]pyridin-2-yl)-2,7-diazaspiro[4.5]...)
Affinity DataKd:  26nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594651(2-(Benzo[d]oxazol-2-yl)-2,7-diazaspiro[4.5]decane-...)
Affinity DataKd:  46nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594652(2-(1-Methyl-1H-benzo[d]imidazol-2-yl)-2,7-diazaspi...)
Affinity DataKd:  30nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594653(2-(Thiazolo[4,5-c]pyridin-2-yl)-2,7-diazaspiro[4.5...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594654(Methyl 2-(6,8-dioxo-2,7-diazaspiro[4.5]decan-2-yl)...)
Affinity DataKd:  8nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594655(Methyl 2-(6,8-dioxo-2,7-diazaspiro[4.5]decan-2-yl)...)
Affinity DataKd:  44nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594656(Methyl 2-(6,8-dioxo-2,7-diazaspiro[4.5]decan-2-yl)...)
Affinity DataKd:  8nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594657(US11584748, Example 24 | tert-Butyl 6-(6,8-dioxo-2...)
Affinity DataKd:  2nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594658(2-(Benzo[d]thiazole-6-carbonyl)-2,7-diazaspiro[4.5...)
Affinity DataKd:  2nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594659(2-(4-Nitropicolinoyl)-2,7-diazaspiro[4.5]decane-6,...)
Affinity DataKd:  19nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594660(2-(2-Oxoindoline-4-carbonyl)-2,7-diazaspiro[4.5]de...)
Affinity DataKd:  47nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594661(Methyl 4-(6,8-dioxo-2,7-diazaspiro[4.5]decane-2-ca...)
Affinity DataKd:  13nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594662(2-(Benzo[d]thiazole-5-carbonyl)-2,7-diazaspiro[4.5...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594663(2-(5-Nitropyridin-2-yl)-2,7-diazaspiro[4.5]decane-...)
Affinity DataKd:  1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594664(2-(2-(Pyridin-3-yl)propanoyl)-2,7-diazaspiro[4.5]d...)
Affinity DataKd:  77nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594665(Methyl 6-(6,8-dioxo-2,7-diazaspiro[4.5]decan-2-yl)...)
Affinity DataKd:  1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594666(2-(5-Nitro-1H-benzo[d]imidazol-2-yl)-2,7-diazaspir...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594667(2-(5-Nitro-1H-benzo[d]imidazol-2-yl)-2,7-diazaspir...)
Affinity DataKd:  5nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594668(2-(1-Acetylindoline-4-carbonyl)-2,7-diazaspiro[4.5...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594669(2-Benzoyl-2,7-diazaspiro[4.5]decane-6,8-dione | US...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594670(N-(3-(6,8-Dioxo-2,7-diazaspiro[4.5]decane-2-carbon...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594671(2-(1H-Indazole-4-carbonyl)-2,7-diazaspiro[4.5]deca...)
Affinity DataKd:  84nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594672(2-(5-Aminopyridin-2-yl-2,7-diazaspiro[4.5]decane-6...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594673(2-(Indoline-4-carbonyl)-2,7-diazaspiro[4.5]decane-...)
Affinity DataKd:  6nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594674(2-(Indoline-6-carbonyl)-2,7-diazaspiro[4.5]decane-...)
Affinity DataKd:  75nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594675(2-(1-Acetylindoline-6-carbonyl)-2,7-diazaspiro[4.5...)
Affinity DataKd:  8nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594676(N-(6-(6,8-Dioxo-2,7-diazaspiro[4.5]decan-2-yl)pyri...)
Affinity DataKd:  12nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594677(2-(Benzofuran-3-carbonyl)-2,7-diazaspiro[4.5]decan...)
Affinity DataKd:  9nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594678(2-(Pyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazasp...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594679(2-(Benzo[d]oxazole-6-carbonyl)-2,7-diazaspiro[4.5]...)
Affinity DataKd:  10nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594680(2-(Indoline-5-carbonyl)-2,7-diazaspiro[4.5]decane-...)
Affinity DataKd:  4nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594681((+)-2-((R)-1,2,3,4-Tetrahydronaphthalene-1-carbony...)
Affinity DataKd:  28nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594682((+2-((S)-1,2,3,4-Tetrahydronaphthalene-1-carbonyl)...)
Affinity DataKd:  14nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM594683(N-(5-(6,8-Dioxo-2,7-diazaspiro[4.5]decane-2-carbon...)
Affinity DataKd:  45nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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