Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 2286
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615666((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(1H-tet...)
Affinity DataIC50:  4nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615641((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(1H-te...)
Affinity DataIC50:  10nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615640((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-([1,2,...)
Affinity DataIC50:  10nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615664((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(6-meth...)
Affinity DataIC50:  10nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM608089((1-cyclopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-meth...)
Affinity DataIC50:  20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM608073((1-cyclopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(4-o...)
Affinity DataIC50:  20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615636((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(5-met...)
Affinity DataIC50:  20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615638((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(4,5,5...)
Affinity DataIC50:  20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615669((5-cyclopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-methy...)
Affinity DataIC50:  20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM608065(US11691968, Example 1 | US20230271952, Example 1 |...)
Affinity DataIC50:  20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615647((1-isopropyl-1H-imidazol-4-yl){(1R,5S,6r)-6-[(4-me...)
Affinity DataIC50:  20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615642((1R,5S,6r)-N-tert-butyl-3-[1-(propan-2-yl)-1H-imid...)
Affinity DataIC50:  20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM608071(US11691968, Example 33 | US20230271952, Example 33...)
Affinity DataIC50:  30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615656((5-isopropyl-1H-pyrazol-3-yl){(1R,5S,6r)-6-[(1S,5S...)
Affinity DataIC50:  30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615650((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-methyl...)
Affinity DataIC50:  30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM608087((1-cyclopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(5,5...)
Affinity DataIC50:  30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615643((1R,5S,6r)-N-tert-butyl-N-methyl-3-[1-(propan-2-yl...)
Affinity DataIC50:  30nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615658(US20230271952, Example 104 | {(1R,5S,6r)-6-[5-(dif...)
Affinity DataIC50:  40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615663(US20230271952, Example 124 | [(1R,5S,6r)-6-(4-cycl...)
Affinity DataIC50:  40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615665((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-([1,2,3...)
Affinity DataIC50:  40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615659((5-isopropyl-1H-pyrazol-3-yl){(1R,5S,6r)-6-[5-meth...)
Affinity DataIC50:  40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615652((1R,5S,6r)-N-tert-butyl-6-methyl-3-[1-(propan-2-yl...)
Affinity DataIC50:  40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615662((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(4-phen...)
Affinity DataIC50:  40nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615667((1R,5S,6r)-N-(propan-2-yl)-3-[5-(propan-2-yl)-1H-p...)
Affinity DataIC50:  50nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615654(US20230271952, Example 90 | [5-(1-cyclopropylethyl...)
Affinity DataIC50:  50nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615660(US20230271952, Example 110 | [(1R,5S,6r)-6-(4-ethy...)
Affinity DataIC50:  50nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615646((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(2-thi...)
Affinity DataIC50:  60nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM608067(US11691968, Example 12 | US20230271952, Example 12...)
Affinity DataIC50:  60nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM608086(US11691968, Example 81 | US20230271952, Example 81...)
Affinity DataIC50:  60nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM608091(US11691968, Example 88 | US20230271952, Example 88...)
Affinity DataIC50:  70nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615670((1R,5S,6r)-N-tert-butyl-6-methyl-3-[5-(propan-2-yl...)
Affinity DataIC50:  90nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615655((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(5-meth...)
Affinity DataIC50:  200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615657((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(5-meth...)
Affinity DataIC50:  200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615631(4-[(1S)-1-(4-{[(1R,5S,6S)-6-(5,5-dimethyl-4,5-dihy...)
Affinity DataIC50:  200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615634(US20230271952, Example 40 | {(1R,5S,6r)-6-[5-(difl...)
Affinity DataIC50:  200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615637((1-isopropyl-1H-imidazol-4-yl)[(1R,5S,6r)-6-(5-met...)
Affinity DataIC50:  200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615639(US20230271952, Example 60 | [(1R,5S,6r)-6-(4-ethyl...)
Affinity DataIC50:  200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615644((1R,5S,6r)-N-(1-cyanocyclopropyl)-N-methyl-3-[1-(p...)
Affinity DataIC50:  200nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615661((5-isopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-(5-meth...)
Affinity DataIC50:  300nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615630(2-[(1S)-1-(4-{[(1R,5S,6S)-6-(5,5-dimethyl-4,5-dihy...)
Affinity DataIC50:  400nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615628(US20230271952, Example 9 | [(1R,5S,6r)-6-(5,5-dime...)
Affinity DataIC50:  400nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615645(US20230271952, Example 75 | cyclopropyl{(1R,5S,6r)...)
Affinity DataIC50:  400nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615668((1R,5S,6r)-N-methyl-N-(1-methylcyclopropyl)-3-[5-(...)
Affinity DataIC50:  800nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM615632(US20230271952, Example 27 | [(1R,5S,6S)-6-(5,5-dim...)
Affinity DataIC50:  1.00E+3nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent