TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 195nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 206nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 356nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 425nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 627nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 669nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 5.72E+3nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair