TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant CDK4/CycD1More data for this Ligand-Target Pair
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibition of recombinant FAKMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
Affinity DataIC50: 5.33E+3nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 5.49E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 5.98E+3nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 5.99E+3nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
Affinity DataIC50: 5.99E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 6.14E+3nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
Affinity DataIC50: 6.68E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
Affinity DataIC50: 6.68E+3nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of recombinant ERBB2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of recombinant COTMore data for this Ligand-Target Pair
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of recombinant EPHB4More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 7.13E+3nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 7.43E+3nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of recombinant CDK4/CycD1More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 8.32E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 8.44E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 8.89E+3nMAssay Description:Inhibition of recombinant FAKMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 8.99E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 9.32E+3nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 9.49E+3nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: 9.99E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant PDGFRbetaMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of recombinant B-RAF-V600E mutantMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of recombinant CDK4/CycD1More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of recombinant PLK1More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Heinrich-Heine-Universitat
Curated by ChEMBL
Heinrich-Heine-Universitat
Curated by ChEMBL
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair