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Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50007908
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513894(CHEMBL4457231)
Affinity DataKi:  120nMAssay Description:Inhibition of West Nile virus NS2B (47 residues)-NS3 (184 residues) protease expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513890(CHEMBL4518710)
Affinity DataKi:  300nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513886(CHEMBL4469970)
Affinity DataKi:  300nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513891(CHEMBL4435875)
Affinity DataKi:  300nMAssay Description:Inhibition of Dengue virus serotype 1 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513888(CHEMBL4439735)
Affinity DataKi:  300nMAssay Description:Inhibition of Dengue virus serotype 1 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513886(CHEMBL4469970)
Affinity DataKi:  400nMAssay Description:Inhibition of Dengue virus serotype 1 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513890(CHEMBL4518710)
Affinity DataKi:  400nMAssay Description:Inhibition of Dengue virus serotype 1 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513891(CHEMBL4435875)
Affinity DataKi:  400nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513889(CHEMBL4586476)
Affinity DataKi:  430nMAssay Description:Inhibition of Zika virus unlinked NS2B-NS3 protease preincubated for 5 mins followed by benzoyl-nKRR-AMC addition and measured every 60 secs for 12 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513897(CHEMBL4541542)
Affinity DataKi:  470nMAssay Description:Inhibition of Zika virus unlinked NS2B-NS3 protease preincubated for 5 mins followed by benzoyl-nKRR-AMC addition and measured every 60 secs for 12 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513890(CHEMBL4518710)
Affinity DataKi:  500nMAssay Description:Inhibition of Dengue virus serotype 3 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513888(CHEMBL4439735)
Affinity DataKi:  500nMAssay Description:Inhibition of Dengue virus serotype 3 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513896(CHEMBL4436979)
Affinity DataKi:  600nMAssay Description:Inhibition of Zika virus unlinked NS2B-NS3 protease preincubated for 5 mins followed by benzoyl-nKRR-AMC addition and measured every 60 secs for 12 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513886(CHEMBL4469970)
Affinity DataKi:  600nMAssay Description:Inhibition of Dengue virus serotype 3 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513891(CHEMBL4435875)
Affinity DataKi:  700nMAssay Description:Inhibition of Dengue virus serotype 3 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513888(CHEMBL4439735)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513888(CHEMBL4439735)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of Dengue virus serotype 4 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513891(CHEMBL4435875)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of Dengue virus serotype 4 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513890(CHEMBL4518710)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of Dengue virus serotype 4 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513886(CHEMBL4469970)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of Dengue virus serotype 4 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513895(CHEMBL1797630)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease preincubated for 1 hr followed by Pyr-RTKR-AMC addition and measured after 30 mins by fluorescence me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50026808(CHEMBL2440341)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated for 15 mins followed by Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr addition and measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513898(CHEMBL4587076)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease preincubated for 10 mins followed by Np-KKR-pNA addition and measured every 5 secs for 2 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513887(CHEMBL4458555)
Affinity DataKi:  1.21E+4nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease expressed in Escherichia coli C41 cells preincubated for 15 mins followed by GRR-AMC addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50026808(CHEMBL2440341)
Affinity DataKi:  9.25E+4nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease preincubated for 15 mins followed by Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr addition and measured for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513893(CHEMBL506092)
Affinity DataIC50:  56nMAssay Description:Inhibition of West Nile virus proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513899(CHEMBL4542342)
Affinity DataIC50:  280nMAssay Description:Inhibition of Zika virus IbH_30656 NS2B (45 to 96 residues)-NS3 (1 to 177 residues) protease expressed in Escherichia coli BL21/Rosetta (DE3) cells p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513892(CHEMBL4549159)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of N-terminal His6-SUMO tagged Zika virus Puerto Rico NS2B-NS3 linked protease expressed in Escherichia coli BL21 Codon Plus (DE3) cells p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513892(CHEMBL4549159)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of N-terminal His6-SUMO tagged Zika virus Puerto Rico NS2B-NS3 unlinked protease expressed in Escherichia coli BL21 Codon Plus (DE3) cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513889(CHEMBL4586476)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Zika virus unlinked NS2B-NS3 protease preincubated for 5 mins followed by benzoyl-nKRR-AMC addition and measured every 60 secs for 12 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513897(CHEMBL4541542)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Zika virus unlinked NS2B-NS3 protease preincubated for 5 mins followed by benzoyl-nKRR-AMC addition and measured every 60 secs for 12 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513892(CHEMBL4549159)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of N-terminal His6-SUMO tagged Zika virus Puerto Rico NS2B-NS3 unlinked protease expressed in Escherichia coli BL21 Codon Plus (DE3) cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(ZIKV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513896(CHEMBL4436979)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Zika virus unlinked NS2B-NS3 protease preincubated for 5 mins followed by benzoyl-nKRR-AMC addition and measured every 60 secs for 12 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513893(CHEMBL506092)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B(40 residues)-NS3 (185 residues) protease preincubated for 30 mins followed by ABz-nKRR-AMC addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513895(CHEMBL1797630)
Affinity DataIC50:  1.87E+4nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease preincubated for 1 hr followed by Pyr-RTKR-AMC addition and measured after 30 mins by fluorescence me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed