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Found 33 Enz. Inhib. hit(s) with all data for entry = 50018126
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  0.0580nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405287(CHEMBL5290583)
Affinity DataIC50:  0.220nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  0.25nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405281(CHEMBL5287438)
Affinity DataIC50:  0.340nMAssay Description:In vitro ability to inhibit HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405285(CHEMBL5269317)
Affinity DataIC50:  0.470nMAssay Description:In vitro ability to inhibit HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405288(CHEMBL5286636)
Affinity DataIC50:  0.540nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405282(CHEMBL5274514)
Affinity DataIC50:  0.550nMAssay Description:In vitro ability to inhibit HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405289(CHEMBL5273197)
Affinity DataIC50:  0.600nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405286(CHEMBL5289304)
Affinity DataIC50:  0.650nMAssay Description:In vitro ability to inhibit HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405281(CHEMBL5287438)
Affinity DataIC50:  2.90nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405290(CHEMBL5266919)
Affinity DataIC50:  3nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405282(CHEMBL5274514)
Affinity DataIC50:  3.5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405287(CHEMBL5290583)
Affinity DataIC50:  6.5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405283(CHEMBL5286055)
Affinity DataIC50:  7nMAssay Description:In vitro ability to inhibit HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405285(CHEMBL5269317)
Affinity DataIC50:  8.30nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405286(CHEMBL5289304)
Affinity DataIC50:  10nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405288(CHEMBL5286636)
Affinity DataIC50:  11nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405284(CHEMBL5272747)
Affinity DataIC50:  13nMAssay Description:In vitro ability to inhibit HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405289(CHEMBL5273197)
Affinity DataIC50:  13nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405283(CHEMBL5286055)
Affinity DataIC50:  20nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405284(CHEMBL5272747)
Affinity DataIC50:  25nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405290(CHEMBL5266919)
Affinity DataIC50:  26nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405281(CHEMBL5287438)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from ratMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  49nMAssay Description:Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium bergheiMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405282(CHEMBL5274514)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from ratMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405283(CHEMBL5286055)
Affinity DataIC50:  87nMAssay Description:Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405289(CHEMBL5273197)
Affinity DataIC50: >100nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from ratMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405288(CHEMBL5286636)
Affinity DataIC50: >100nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405287(CHEMBL5290583)
Affinity DataIC50: >100nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Mycobacterium lufuMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405286(CHEMBL5289304)
Affinity DataIC50: >100nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from ratMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405285(CHEMBL5269317)
Affinity DataIC50: >100nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Mycobacterium lufuMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405284(CHEMBL5272747)
Affinity DataIC50: >100nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from ratMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50405290(CHEMBL5266919)
Affinity DataIC50: >100nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed