Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50018879
LigandPNGBDBM50613593(CHEMBL5285324)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50613594(CHEMBL5275755)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50613595(CHEMBL5272100)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50613596(CHEMBL5272356)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50613597(CHEMBL5270626)
Affinity DataIC50: <1nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
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TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50305548(1-(4-(4-(3,6-dihydro-2H-pyran-4-yl)-1-(2,2,2-trifl...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
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TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50613599(CHEMBL5273296)
Affinity DataIC50:  5nMAssay Description:Inhibition of SYK (unknown origin) using biotinylated EDPDYEWPSA as substrate incubated for 30 mins in presence of 33P-ATP by Scintillation Proximity...More data for this Ligand-Target Pair
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TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50613600(CHEMBL5285207)
Affinity DataIC50:  5nMAssay Description:Inhibition of SYK (unknown origin) using biotinylated EDPDYEWPSA as substrate incubated for 30 mins in presence of 33P-ATP by Scintillation Proximity...More data for this Ligand-Target Pair
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TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50613601(CHEMBL5270442)
Affinity DataIC50:  5nMAssay Description:Inhibition of SYK (unknown origin) using biotinylated EDPDYEWPSA as substrate incubated for 30 mins in presence of 33P-ATP by Scintillation Proximity...More data for this Ligand-Target Pair
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TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50235342(CHEMBL319467 | NU-6102)
Affinity DataIC50:  5nMAssay Description:Inhibition of human CDK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50613602(CHEMBL5268541)
Affinity DataIC50:  5nMAssay Description:Inhibition of SYK (unknown origin) using biotinylated EDPDYEWPSA as substrate incubated for 30 mins in presence of 33P-ATP by Scintillation Proximity...More data for this Ligand-Target Pair
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TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50613598(CHEMBL5283028)
Affinity DataIC50:  5nMAssay Description:Inhibition of SYK (unknown origin) using biotinylated EDPDYEWPSA as substrate incubated for 30 mins in presence of 33P-ATP by Scintillation Proximity...More data for this Ligand-Target Pair
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LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50:  9nMAssay Description:Inhibition of human PI3K-delta using PIP2 as substrate in presence of gamma[32P]ATPMore data for this Ligand-Target Pair
LigandPNGBDBM50613584(CHEMBL5280278)
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3K-p110alpha (unknown origin) incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50613585(CHEMBL5274644)
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3K-p110alpha (unknown origin) incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50059635(CHEMBL3393066)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant PI3K p110alpha/p85 (unknown origin) incubated for 1 hr in presence of gamma[33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM150174(US8980901, 93 | US9149477, Compound 93)
Affinity DataIC50:  12nMAssay Description:Inhibition of human PI3K-delta using PIP2 as substrate in presence of gamma[32P]ATPMore data for this Ligand-Target Pair
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LigandPNGBDBM104485(US8586597, 99 | USRE44599, 98)
Affinity DataIC50:  16nMAssay Description:Inhibition of human PI3K-delta using PIP2 as substrate in presence of gamma[32P]ATPMore data for this Ligand-Target Pair
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LigandPNGBDBM50613587(CHEMBL5288282)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) using histone as substrate incubated for 30 mins in presence of gamma[33P]ATP by digital imaging analysi...More data for this Ligand-Target Pair
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LigandPNGBDBM50613588(CHEMBL5272545)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) using histone as substrate incubated for 30 mins in presence of gamma[33P]ATP by digital imaging analysi...More data for this Ligand-Target Pair
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LigandPNGBDBM50613590(CHEMBL5283615)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) using histone as substrate incubated for 30 mins in presence of gamma[33P]ATP by digital imaging analysi...More data for this Ligand-Target Pair
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LigandPNGBDBM50613589(CHEMBL5283233)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) using histone as substrate incubated for 30 mins in presence of gamma[33P]ATP by digital imaging analysi...More data for this Ligand-Target Pair
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LigandPNGBDBM50613586(CHEMBL5290495)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) using histone as substrate incubated for 30 mins in presence of gamma[33P]ATP by digital imaging analysi...More data for this Ligand-Target Pair
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LigandPNGBDBM182846(US9149477, Compound 174)
Affinity DataIC50:  26nMAssay Description:Inhibition of human PI3K-delta using PIP2 as substrate in presence of gamma[32P]ATPMore data for this Ligand-Target Pair
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LigandPNGBDBM50613592(CHEMBL5287410)
Affinity DataIC50: <30nMAssay Description:Inhibition of PI3K-delta (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50613591(CHEMBL5268742)
Affinity DataIC50: <30nMAssay Description:Inhibition of PI3K-delta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50059635(CHEMBL3393066)
Affinity DataIC50:  39nMAssay Description:Inhibition of mTOR (unknown origin) incubated for 1 hr in presence of gamma[33P]ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM104486(US8586597, 101 | USRE44599, 117)
Affinity DataIC50:  45nMAssay Description:Inhibition of human PI3K-delta using PIP2 as substrate in presence of gamma[32P]ATPMore data for this Ligand-Target Pair
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LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: <50nMAssay Description:Inhibition of human CDK2/cyclinA using histone H1 as substrate incubated for 30 mins in presence of gamma[32P]ATP by phosphoimaging analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50546239(CHEMBL103579)
Affinity DataIC50: <50nMAssay Description:Inhibition of human CDK2/cyclinA using histone H1 as substrate incubated for 30 mins in presence of gamma[32P]ATP by phosphoimaging analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: <50nMAssay Description:Inhibition of human CDK2/cyclinA using histone H1 as substrate incubated for 30 mins in presence of gamma[32P]ATP by phosphoimaging analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50113725(2-Chloro-5-[2-(1-hydroxymethyl-2-methyl-propylamin...)
Affinity DataIC50: <50nMAssay Description:Inhibition of human CDK2/cyclinA using histone H1 as substrate incubated for 30 mins in presence of gamma[32P]ATP by phosphoimaging analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50235040(AMINOPURVALANOL | CHEBI:38937)
Affinity DataIC50: <50nMAssay Description:Inhibition of human CDK2/cyclinA using histone H1 as substrate incubated for 30 mins in presence of gamma[32P]ATP by phosphoimaging analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50113693(2-[6-(3-Amino-4-chloro-phenylamino)-9-isopropyl-9H...)
Affinity DataIC50: <50nMAssay Description:Inhibition of human CDK2/cyclinA using histone H1 as substrate incubated for 30 mins in presence of gamma[32P]ATP by phosphoimaging analysisMore data for this Ligand-Target Pair
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