Found 7 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50174298'
Affinity DataKi: 1.30nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity against mouse 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity against human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human microsomal 11beta-HSD1 assessed as inhibition of conversion of radiolabeled cortisone to radiolabeled cortisol by cell-based assa...More data for this Ligand-Target Pair