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Found 2 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50526295'
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526295(CHEMBL4469087)
Affinity DataIC50:  85nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50526295(CHEMBL4469087)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of full-length C-terminal NanoLuc-tagged ALK (unknown origin) expressed in human HEK293 cells after 2 hrs by NanoBRET target engagement as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed