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Report error Found 6 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM50313079'
TargetAcetylcholinesterase(Bovine)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataKi:  1.97E+4nMAssay Description:Inhibitory activity against Acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bovine)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  50nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Human)
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Human)
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Human)
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  4.00E+4nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Human)
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank