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Found 3 Enz. Inhib. hit(s) with Target = 'Angiopoietin-1 receptor' and Ligand = 'BDBM50266148'
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50266148(CHEMBL465793 | N-(4-(3-(2-(methylamino)pyrimidin-4...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Tie2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50266148(CHEMBL465793 | N-(4-(3-(2-(methylamino)pyrimidin-4...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50266148(CHEMBL465793 | N-(4-(3-(2-(methylamino)pyrimidin-4...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Tie2 autophosphorylation in human Ea.hy926 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed