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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM12986'
TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12986(4-(4-methylpiperazin-1-yl)-N-{5-[(2S)-2-phenylprop...)
Affinity DataIC50:  452nMAssay Description:Inhibition of aurora A kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12986(4-(4-methylpiperazin-1-yl)-N-{5-[(2S)-2-phenylprop...)
Affinity DataIC50:  452nMpH: 7.5 T: 22°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed