Report error Found 3 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50394785'
Affinity DataIC50: 6.10nMAssay Description:Inhibition of Aurora kinase B-mediated histone H3 Ser10 phosphorylation in human HCT116 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:Binding affinity to Aurora kinase B catalytic domain by competition binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Inhibition of Aurora kinase B in human HCT116 cells assessed as induction of 8N polyploidyMore data for this Ligand-Target Pair