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Found 4 Enz. Inhib. hit(s) with Target = 'Baculoviral IAP repeat-containing protein 2' and Ligand = 'BDBM50388975'
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50388975(CHEMBL2063869)
Affinity DataKi:  17nMAssay Description:Displacement of 5-FAM-conjugated AVP-diPhe-FAM from cIAP1 BIR3 domain after 30 mins by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50388975(CHEMBL2063869)
Affinity DataKi:  1.45E+4nMAssay Description:Displacement of AVPFAK(5-FAM)K (Hid-FAM) from cIAP1 BIR2 domain after 30 mins by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50388975(CHEMBL2063869)
Affinity DataIC50:  10nMAssay Description:Displacement of AVPIAQKSEK-biotin from cIAP1 BIR3 (unknown origin) after 1 hr by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50388975(CHEMBL2063869)
Affinity DataKd:  17nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed