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Report error Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM29805'
TargetBeta-secretase 1(Human)
Gsk

LigandPNGBDBM29805(sulfone tricyclic analogue, 18)
Affinity DataIC50:  8nMpH: 4.5 T: 22°CAssay Description:Enzyme activity and inhibition were assayed using a fluorescent FAM-[SEVNLDAEFK]-TAMRA substrate. Control reactions with no enzyme were included in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed