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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50313805'
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50313805((1R,3S)-N-((2S,3S)-3-hydroxy-4-(3-isopropylbenzyla...)
Affinity DataIC50:  25nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50313805((1R,3S)-N-((2S,3S)-3-hydroxy-4-(3-isopropylbenzyla...)
Affinity DataIC50:  130nMAssay Description:Inhibition of BACE1 expressed in CHO cells co-transfected with human APP assessed as inhibition of cellular release of Abeta 40 after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed