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Found 2 Enz. Inhib. hit(s) with Target = 'Bifunctional dihydrofolate reductase-thymidylate synthase' and Ligand = 'BDBM50452173'
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50452173(CHEMBL1939368)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of Plasmodium falciparum DHFR using DHF as substrate preincubated for 15 mins followed DHF addition measured after 15 mins by spectrophoto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50452173(CHEMBL1939368)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of Plasmodium falciparum DHFRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed