Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Broad substrate specificity ATP-binding cassette transporter ABCG2' and Ligand = 'BDBM50208611'
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital

Curated by ChEMBL
LigandPNGBDBM50208611((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of ABCG2 in mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as increase in intracellular mitoxantrone accumu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital

Curated by ChEMBL
LigandPNGBDBM50208611((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibition of ABCG2 in becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as increase in intracellular mitoxantrone accumulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed