Found 2 Enz. Inhib. hit(s) with Target = 'Broad substrate specificity ATP-binding cassette transporter ABCG2' and Ligand = 'BDBM50208611'
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of ABCG2 in mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as increase in intracellular mitoxantrone accumu...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of ABCG2 in becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as increase in intracellular mitoxantrone accumulat...More data for this Ligand-Target Pair