Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50315994'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(CHEMBL1091604 | N-(2-((1S,2R,4R)-4-(isopropyl(meth...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(CHEMBL1091604 | N-(2-((1S,2R,4R)-4-(isopropyl(meth...)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:Inhibition of [125I]hMCP1 binding to CCR2 in human PBMC incubated for 30 mins at room temperatureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(CHEMBL1091604 | N-(2-((1S,2R,4R)-4-(isopropyl(meth...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]MCP-1 from CCR2 in human PMBCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(CHEMBL1091604 | N-(2-((1S,2R,4R)-4-(isopropyl(meth...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity against CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(CHEMBL1091604 | N-(2-((1S,2R,4R)-4-(isopropyl(meth...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 45 mins in presence of 0.1 M bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed