Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Ligand = 'BDBM50190513'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed