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Found 3 Enz. Inhib. hit(s) with Target = 'CTP synthase 1' and Ligand = 'BDBM50609670'
TargetCTP synthase 1(Homo sapiens)TBA
LigandPNGBDBM50609670(CHEMBL5277468)
Affinity DataIC50:  42nMAssay Description:Inhibition of human CTPS1 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCTP synthase 1(Mus musculus)TBA
LigandPNGBDBM50609670(CHEMBL5277468)
Affinity DataIC50:  53nMAssay Description:Inhibition of mouse CTPS1 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCTP synthase 1(Homo sapiens)TBA
LigandPNGBDBM50609670(CHEMBL5277468)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of C-terminal FLAG-His8-tagged full length human CTPS1 preincubated for 10 mins followed by substrate addition by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed