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Found 3 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM239075'
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataKi:  78nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataKi:  78.3nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataKi:  251nM ΔG°:  -37.7kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
In DepthDetails US Patent