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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Ligand = 'BDBM225148'
TargetCathepsin S(Mouse)
Astellas Pharma

US Patent
LigandPNGBDBM225148(US9328118, 54)
Affinity DataIC50:  0.940nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCathepsin S(Human)
Astellas Pharma

US Patent
LigandPNGBDBM225148(US9328118, 54)
Affinity DataIC50:  3.90nMAssay Description:5 μL of a human cathepsin S enzyme (R&D1183-CY-010) was added to a 96-well plate so as to be 20 ng/well. Next, 10-fold dilution of the test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent