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Found 4 Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50149669'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149669(CHEMBL183148 | [2,5-Dimethyl-3-(3-methyl-5-nitro-p...)
Affinity DataKi:  9.10nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149669(CHEMBL183148 | [2,5-Dimethyl-3-(3-methyl-5-nitro-p...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149669(CHEMBL183148 | [2,5-Dimethyl-3-(3-methyl-5-nitro-p...)
Affinity DataIC50:  180nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149669(CHEMBL183148 | [2,5-Dimethyl-3-(3-methyl-5-nitro-p...)
Affinity DataIC50:  180nMAssay Description:Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed