Found 2 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 2/G1/S-specific cyclin-E1' and Ligand = 'BDBM5670' TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute
Curated by ChEMBL
University of South Australia Cancer Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged CDK2/Cyclin E (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate m...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of South Australia Cancer Research Institute
Curated by ChEMBL
University of South Australia Cancer Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
