Affinity DataKi: 1.20nMAssay Description:Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4More data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D4.4More data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Binding Affinity was tested on low Affinity Site of Dopamine receptor D4.4More data for this Ligand-Target Pair
Affinity DataKi: 97nMAssay Description:Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D4.4More data for this Ligand-Target Pair
Affinity DataKi: 3.31E+3nMAssay Description:Inhibitory constant for [3H]YM-09151-2 binding to Dopamine receptor D2-like in porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 269nMAssay Description:Agonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as beta arrestin-2 recruitment measured after 2.5 mins by BRET ass...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Displacement of [3H]NMS from human muscarinic M4 receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 91nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at D4R (unknown origin) expressed in HEK293 cells assessed as effect on cAMP accumulation incubated for 10 mins by Gi-cAMP Glosensor...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as G0 protein activation measured after 2.5 mins by BRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as Gi protein activation measured after 2.5 mins by BRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at ferret D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Agonist activity at rat D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair