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Found 8 Enz. Inhib. hit(s) with Target = 'D-3-phosphoglycerate dehydrogenase' and Ligand = 'BDBM50230352'
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataKi:  2.70E+4nMAssay Description:Non-competitive inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataKi:  4.00E+4nMAssay Description:Non-competitive inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of PHGDH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50:  7.17E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230352(CHEMBL4086943)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed