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Report error Found 8 Enz. Inhib. hit(s) with Target = 'Delta-type opioid receptor' and Ligand = 'BDBM50077066'
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataKi:  11nMAssay Description:In vitro binding affinity to Opioid receptor delta 1 in rat brain membranes by [3H]DADLE (Tyr-D-Ala-Gly-Phe-D-Leu) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  5nMAssay Description:Compound was tested for inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  8nMAssay Description:Binding inhibition of [3H]- -naltrindole (0.15 nM) to membranes in CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  16nMAssay Description:Binding affinity against human opioid receptor delta 1 using [125I]-[D-Ala2]-deltorphin II as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataEC50:  33nMAssay Description:Agonist potency was measured using GTP gamma-[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed