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Found 2 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM379703'
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM379703(US9926281, Compound 405 | US9926281, Compound 422)
Affinity DataIC50: >4.00E+3nMAssay Description:TACE:The basis for the assay is the cleavage of the substrate 5FAM-LAQAVRSSSRK-5TAMRA (SEQ ID No 3) (Anaspec, custom 34891) by human TACE (R&D SYSTEM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM379703(US9926281, Compound 405 | US9926281, Compound 422)
Affinity DataIC50: >4.00E+3nMAssay Description:TACE:The basis for the assay is the cleavage of the substrate 5FAM-LAQAVRSSSRK-5TAMRA (SEQ ID No 3) (Anaspec, custom 34891) by human TACE (R&D SYSTEM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent