Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM535402'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM535402((3R)-3-(4-chlorophenyl)-2-[(5- chloropyridin-2-yl)...)
Affinity DataIC50:  0.930nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM535402((3R)-3-(4-chlorophenyl)-2-[(5- chloropyridin-2-yl)...)
Affinity DataIC50:  0.930nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent