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Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM628691'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM628691(6-{[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[1-hydroxy-...)
Affinity DataIC50:  0.640nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM628691(6-{[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[1-hydroxy-...)
Affinity DataIC50:  11nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent