Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Endothelin receptor type B' and Ligand = 'BDBM50105051'
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50105051(CHEMBL112624 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  12nMAssay Description:Displacement of [I125]ET1 from recombinant ETB receptor expressed in CHO cells after 2 hrs by TopCount analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50105051(CHEMBL112624 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at ET-B receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50105051(CHEMBL112624 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  41nMAssay Description:Displacement of 125I-ET1 from pig ETB receptor transfected in grivet COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50105051(CHEMBL112624 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  41nMAssay Description:Displacement of 125I-ET1 from pig ETB receptor transfected in grivet COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed