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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Enoyl-[acyl-carrier-protein] reductase [NADH]' and Ligand = 'BDBM190656'
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis)
University of Wurzburg

LigandPNGBDBM190656(PT424)
Affinity DataKi:  8.00E+3nM ΔG°:  -29.1kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis)
University of Wurzburg

LigandPNGBDBM190656(PT424)
Affinity DataKi:  1.60E+4nM ΔG°:  -27.4kJ/molepH: 8.0 T: 25°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis)
University of Wurzburg

LigandPNGBDBM190656(PT424)
Affinity DataIC50:  2.10E+4nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed