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Found 5 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50613695'
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613695(CHEMBL5274166)
Affinity DataKi:  0.350nMAssay Description:Inhibition of human EGFR T790M/del (746 to 750 residues) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as subs...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613695(CHEMBL5274166)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613695(CHEMBL5274166)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human EGFR del (746 to 750) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for ...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613695(CHEMBL5274166)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human EGFR L858R mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as substrate preincubated for 30 ...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613695(CHEMBL5274166)
Affinity DataKi:  7.80nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
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