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Found 4 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50437049'
TargetEstrogen receptor(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437049(CHEMBL2403355)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity to GST-tagged human ER alpha ligand-binding domain by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437049(CHEMBL2403355)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437049(CHEMBL2403355)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as reduction in E2-induced ER-alpha-mediated transcrip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437049(CHEMBL2403355)
Affinity DataEC50:  28nMAssay Description:Selective estrogen receptor down-regulator activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ERalph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed